Prefer natural. But sometimes the fillers, botox, lips, and implants are done in such a way as to enhance what nature give them in a natural way--that I don't mind.
For example, Agatha Vega's implants aren't overdone and if not for the scars, you'd probably wonder if they are real or implants. Another example, Yumi Sin--I'm not sure if they're real or implants--even though they aren't overly huge, very few Asian women I've been with IRL (and there's been at least a couple dozen), have natural breasts that large. My wife's breasts a slight bit smaller than Yumi Sin's, and she's Asian, and they are natural, so it makes me wonder if Yumi's are real or natural. (BTW, while my wife does get some botox and fillers, I usually go with her and talk her out of extremes--she has perfect lips, but she wanted those horrible looking filled lips).
On the other hand, for examples, I think Morgan Lee and Victoria June (among others) ruined their looks with the work they had done. (Sorry if you're reading this Morgan and Victoria.)
This is probably TMI, so I may come back and edit down